Domestic biochip technology has profound significance in R&D

In order to better understand the latest research and application trends and development directions of biochips at home and abroad, promote the exchange and communication of experiences in biotechnology and life science related industries, and increase the conversion rate of domestic biochip applications, recently, the Ministry of Science and Technology, Tsinghua University, and China Medical Biology The Technical Association, China Biotechnology Association of Biotechnology and Biochip Beijing National Engineering Research Center (and Boao Biotechnology Co., Ltd.) held a conference on the application of biochips in medical and food security. A new bright spot emerged in the conference. The attending meeting of the university leader of Ningbo University led by President Feng Zhimin and the Dean of Life Sciences and Bioengineering Institute Li Taiwu, together with Professor Jing Jing, Director of the Beijing National Engineering Research Center for Biochips, established a biochip in Ningbo, Zhejiang Province. The National Marine Research Center of Beijing National Engineering Research Center held talks and signed a cooperation agreement on April 29th.

Biochip is a high-tech product that has rapidly developed in the field of life sciences in the late 1980s. It mainly refers to a microbiochemical analysis system constructed on the surface of a solid polymer chip through microfabrication and microelectronics technology. Realize the accurate, rapid and large amount of information detection of cells, proteins, DNA and other biological components. Commonly used biochips fall into three categories: gene chips, protein chips, and chip laboratories. The main features of biochips are high throughput, miniaturization and automation. Thousands of densely packed molecular microarrays integrated on a chip can analyze a large number of biomolecules in a short period of time, enabling people to quickly and accurately obtain biological information in samples. The efficiency is hundreds of times that of conventional detection methods. . It will be another far-reaching scientific and technological revolution following large-scale integrated circuits.

For the high-tech of biochips, governments, science and technology circles, and industrial circles all over the world attach great importance to them, and invest a lot of manpower, material resources, and financial resources to conduct R&D and industrialization. Since 1997, China has also begun to increase input in the field of biochips. Especially since 2000, China’s biochip technology and industrialization have achieved even more under the personal care and approval of Zhu Rongji, the main leader of the State Council. Rapid development by leaps and bounds. The National Development and Reform Commission was submitted to the State Council for approval, with Tsinghua University as the main initiator, and Huazhong University of Science and Technology, the Chinese Academy of Medical Sciences, and the Academy of Military Medical Sciences participated in the joint participation of three research institutes, concentrating on the establishment of advantageous technical, human, and financial resources across the country. Beijing National Engineering Research Center for Biochips (cum-Bao Bio Inc.). The National Center for Biochip Beijing (Bao Bio) has now become China's largest research, development, and industrialization base in the field of biochips with the largest scale, strongest strength, and most advanced technology. At present, Boao Bio total assets of 541 million yuan, with 24,000 square meters of research and development, production and operating facilities, since 2003 began to bring products to the market, sales have maintained an annual growth rate of 100% to 300%. Many of these products have filled the gaps in the domestic market and some of the products are internationally leading and have been exported to 12 countries in Europe and the United States and have received wide acclaim.

Since the preparation of the National Center for Biochips, many leaders of countries have been very concerned about the development of the center, either visiting the site or hearing reports or making important instructions. Chairman of the Standing Committee of the National People's Congress, former Chairman of the Standing Committee of the People's Republic of China, Honorary Chairman of the China Association for Science and Technology Zhou Guangzhao, Academician Chen Yu, Minister of Education Zhou Ji, Deputy Minister of Science and Technology Li Xueyong, Cheng Jinpei, Ma Songde, Deputy Director of the General Administration of Quality Supervision, Inspection and Quarantine Wei Chuanzhong, Yunnan Provincial Party Committee Secretary Bai Enpei, then governor Xu Rongkai, Jiangxi Provincial Party Committee Secretary Meng Jianzhu, Tsinghua University President Gu Binglin, Nankai University President Rao Zihe and academicians have visited the National Center for Biochips several times to inspect and guide the work.

In the 21st century, in the face of the common problems of population growth, shortage of resources, and environmental degradation, the international community generally believes that the ocean is a strategic point for solving the above problems. The most critical strategic material for humanity can be obtained from the ocean. Marine biotechnology has thus become a competition for the 21st century. Countries around the world have formulated the “Marine Biotechnology Program”. Marine aquaculture, marine drugs, new functional genes, and environmental protection have become hot spots in international competition.

Aiming at the important economic aquatic animals and plants in the coastal areas of Zhejiang Province, basic research is applied, a reasonable database of germplasm resources is established, and germplasm lines and genetic biochemical markers related to good traits are established; development and introduction of new suitable for aquaculture in Zhejiang sea area New varieties with important economic development potential; Finding out the types and resource characteristics of the main active resources along the coast of Zhejiang Province, and establishing relevant drug source biological resource pools and activity databases for the sustainable development of marine drugs, and having reasonable exploitation and utilization of marine biological resources. Important guidance. Marine Marine Minute Core aims to focus on the functional genomics of mariculture animals and their pathogens, and uses biochips as the main technical means to screen and identify functional genes closely related to the growth regulation, immunity and disease resistance of important marine aquaculture animals. New types of highly efficient and safe marine growth animal growth promoters, high-quality feed additives or immune enhancers have produced a number of marine genetic engineering products that are geared to the country’s major needs, have distinctive resource features and unique mechanisms of action, have independent intellectual property rights, and have a promising international market. Candidate product functional genes, etc., make the comprehensive capabilities of research and development of marine life functional genes and products in China approach or reach the advanced level of developed countries, improve the level of research and development and innovation, increase the market competitiveness of related products, and create a higher economy and society. benefit.

It is reported that the establishment of the Biochip Beijing National Engineering Research Center Marine Biology Center means that the Beijing National Engineering Research Center for Biochips and Ningbo University will carry out strategic cooperation in the field of marine biology on basic research, product development and industrialization of biochips.

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